Immune amegakaryocytic thrombocytopenia of the newborn: association with anti-HLA-A2.
نویسندگان
چکیده
منابع مشابه
Anti-CD20 Antibody is Effective in the Patient with Refractory Amegakaryocytic Thrombocytopenia, 25 Months Follow up
Amegakaryocytic thrombocytopenia (AMT) is a rare cause of acquired thrombocytopenia. The pathogenesis and treatment of AMT is not clearly known. Here we demonstrate a 50-year-old man presented with the clinical manifestations of severe thrombocytopenia (7000 platelets/µl) with a marked decrease to absent of megakaryocytes in the bone marrow. The patient did not respond to intravenous immunoglob...
متن کاملanti-cd20 antibody is effective in the patient with refractory amegakaryocytic thrombocytopenia, 25 months follow up.
amegakaryocytic thrombocytopenia (amt) is a rare cause of acquired thrombocytopenia. the pathogenesis and treatment of amt is not clearly known. here we demonstrate a 50-year-old man presented with the clinical manifestations of severe thrombocytopenia (7000 platelets/µl) with a marked decrease to absent of megakaryocytes in the bone marrow. the patient did not respond to intravenous immunoglob...
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During the year 2016, in United States, it is estimated that 53,070 new cases of pancreatic adenocarcinoma will be diagnosed, out of which, 41, 780 people are expected to die of pancreatic cancer [1]. In contrast to declining trend of incidence for most cancers, incidence of pancreatic cancer tends to be rising from 2003 to 2012 because of increasing prevalence of obesity, aging population and ...
متن کاملNeonatal alloimmune thrombocytopenia due to HLA-A2 antibody.
A male, full-term baby with thrombocytopenia was born by a G3P2A1 mother who was not associated with autoimmune disease. Platelet antibody screening was positive by using lymphocytotoxicity test, platelet suspension immunofluorescence test and solid-phase red cell adherence test. The identified HLA antibody was of A2 specificity. It was confirmed by testing the mother's and the baby's sera agai...
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We studied a patient with a rare complication of amegakaryocytic thrombocytopenia (AMT) associated with systemic lupus erythematosus (SLE). To investigate the underlying pathogenesis of AMT, the effects of peripheral blood T cells and serum on human megakaryocyte progenitor cells were studied using in vitro coculture techniques. Mononuclear bone marrow cells (2 X 10(5) from normal donors produc...
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ژورنال
عنوان ژورنال: Journal of Clinical Pathology
سال: 1987
ISSN: 0021-9746
DOI: 10.1136/jcp.40.3.258